User blog comment:Ohatsu/game modes/@comment-24458380-20150621182044

Bitterblack Isle will only completely reset to its Pre-Daimon state when you hand over the 20 Wakestones to Quince and slay the Seneschal.

During my playthroughs, the only hesitation I ever experience is : Do I really wanna slay the Seneshal now, or should I farm Bitterblack more before I do it ?

The treasure you can find in Post-Daimon Bitterblack is much more powerful than the treasure in Pre-Daimon Bitterblack Isle. And the two shortcuts through the Corridor of Emptiness and the Corridor of the Hallowed re-close when Bitterblack resets. So once you slay the Seneschal, you'll actually have to work your through Pre-Daimon Bitterblack again to get to Post-Daimon Bitterblack.

Perhaps it's not a big deal to some players, but it's something to consider.

By the way, "Pre-Daimon" refers to the easier version of the dungeon before you slay him for the first time, and "Post-Daimon" refers to the harder version of the dungeon after he's slain for the first time.

I hope this answers your question !